Quantitative Scoring Methods
1
Score |
0 |
1+ |
2+ |
3+ |
4+ |
Positive Cells |
<10% |
10-25% |
25-50% |
50-75% |
>75% |
2
Score |
0 |
1 |
2 |
3 |
4 |
Positive Cells |
negative |
few nuclei |
10% |
10-50% |
>50% |
3
Score |
low level |
high level |
|
|
|
Positive Cells |
<20% |
>20% |
|
|
|
4
Score |
1 |
2 |
3 |
|
|
Intensity of Staining |
weak staining |
moderate staining |
strong staining |
|
|
5 Quick score (Q):
Results are scored by multiplying the percentage of positive cells
(P) by the intensity (I).
Formula: Q = P x I; Maximum = 300
References
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Alvord WG, Amorosi A, Nesi G, Saieva C, Masala G, Fraumeni JF Jr,
Rice JM. Genetic and immunohistochemical analyses of p53
independently predict regional metastasis of gastric cancers. Cancer
Epidemiol Biomarkers Prev. 2000 Jun;9(6):631-633
Charafe-Jauffret E, Tarpin C, Bardou VJ,
Bertucci F, Ginestier C, Braud AC, Puig B, Geneix J, Hassoun J,
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