Problems in Histopathological Technique
IMVS Division of
Woodville, South Australia 5011
DID YOU KNOW 13?
Did you know that nucleoli stain blue after Zenker
Nucleoli are composed mainly of RNA and usually stain red after
eosin staining in a Haematoxylin and Eosin. So it is unusual that
after Zenker fixation they stain blue. Try it out on a piece of
tissue from a tumour, where cells are very active and you should
find many blue nucleoli but they can sometimes be difficult to
detect in a nucleus that also stains the same colour.
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© Roy C. Ellis 2002